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Results. —Overall, patients with dementia and stroke had a higher APOE ϵ4 allele frequency than controls. Compared with APOE e3 homozygote individuals, APOE ϵ4 homozy
. We studied the relationship between ApoE ϵ4 genotype and the deposition of Aβ in temporal lobe tissue from patients who underwent temporal lobectomy for intractable epile
Possession of one or more copies of the apolipoprotein E (APOE) ϵ4 allele is a known risk factor for Alzheimer’s disease (AD), but it is uncertain whether the ϵ4 allele is asso
The APOE ϵ4 allele was found in 83 (29.4%) patients. Although preexisting cognitive impairment was present in 105 (37.2%) and postoperative cognitive dysfunction in 33 (12%
In participants who were homozygous for the ϵ4 allele, the odds of cardiac dysfunction was increased 3-fold (OR, 3.1; 95% CI, 1.2–8.1), whereas the odds of cardiac dysfunction
Shu H, Cerebral cortex (New York, N.Y. : 1991), The apolipoprotein E (APOE) ϵ4 allele is a confirmed genetic risk factor and the APOE ϵ2 allele is a protective factor related to
. The ϵ4 allele of apolipoprotein E (APO E) has been strongly associated with familial and late‐onset AD. We therefore compared the APO E allele frequencies in a group of 14
Li GSilverman JMAltstiel LD et al. Apolipoprotein E-ϵ4 allele and familial risk in Alzheimer's disease. Genet Epidemiol. 1996;13285- 298Google ScholarCrossref Edland SDSilv
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